The ingredient narratives reshaping clean beauty.
Madecassoside
aka teca · asiaticoside · madecassic acid · asiatic acid
The most active triterpenoid isolated from centella asiatica (cica). Where 'centella' on a label can mean anything, madecassoside is the standardized molecule with the strongest data on barrier repair, post-procedure recovery, and TGF-β-mediated collagen synthesis. La Roche-Posay Cicaplast (and dermatology's broader 'cica' category) is built on it; Dr. Jart+ Cicapair, Skin1004 Madagascar Centella, and Purito's centella ranges drive K-beauty side. The 2025 conversation is moving from 'centella' to 'madecassoside %' on the label.
- accelerates wound healing and post-procedure repair (clinical-grade evidence)
- anti-inflammatory via NF-κB suppression
- stimulates type I and III collagen — the 'micro-anti-aging' angle
- post-procedure recovery (LRP Cicaplast)
- barrier-repair creams
- sensitive-skin daily moisturizers
Effective at 0.1–1% in serums and creams; LRP Cicaplast uses 0.2% madecassoside as its hero. Stacks well with panthenol (LRP's signature combo), ceramides, and centella's sister molecules (asiaticoside, asiatic acid, madecassic acid — together the 'TECA' complex).
'Centella extract' on a label without madecassoside spec gives no efficacy guarantee — supplier variability is enormous.
Strongly trusted across both clean and clinical camps.
The ingredient narratives reshaping clean beauty.
Madecassoside
aka teca · asiaticoside · madecassic acid · asiatic acid
The most active triterpenoid isolated from centella asiatica (cica). Where 'centella' on a label can mean anything, madecassoside is the standardized molecule with the strongest data on barrier repair, post-procedure recovery, and TGF-β-mediated collagen synthesis. La Roche-Posay Cicaplast (and dermatology's broader 'cica' category) is built on it; Dr. Jart+ Cicapair, Skin1004 Madagascar Centella, and Purito's centella ranges drive K-beauty side. The 2025 conversation is moving from 'centella' to 'madecassoside %' on the label.
- accelerates wound healing and post-procedure repair (clinical-grade evidence)
- anti-inflammatory via NF-κB suppression
- stimulates type I and III collagen — the 'micro-anti-aging' angle
- post-procedure recovery (LRP Cicaplast)
- barrier-repair creams
- sensitive-skin daily moisturizers
Effective at 0.1–1% in serums and creams; LRP Cicaplast uses 0.2% madecassoside as its hero. Stacks well with panthenol (LRP's signature combo), ceramides, and centella's sister molecules (asiaticoside, asiatic acid, madecassic acid — together the 'TECA' complex).
'Centella extract' on a label without madecassoside spec gives no efficacy guarantee — supplier variability is enormous.
Strongly trusted across both clean and clinical camps.